Dysplastic nevus syndrome: A phenotypic association of sporadic cutaneous melanoma
نویسندگان
چکیده
منابع مشابه
Hereditary dysplastic nevus syndrome: lymphoid cell ultraviolet hypermutability in association with increased melanoma susceptibility.
The hereditary dysplastic nevus syndrome (DNS) is a well-characterized disorder in which affected individuals have increased numbers of premalignant (dysplastic) nevi and a markedly increased risk of developing cutaneous melanoma. Seeking evidence of a systemic disorder in DNS, we examined the effect of ultraviolet radiation on cultured lymphoid cells. Epstein-Barr virus-transformed lymphoblast...
متن کاملDysplastic nevus (atypical nevus).
Atypical nevum (dysplastic) is considered an important factor associated with increased risk of developing cutaneous melanoma. It is believed that atypical nevi are precursor lesions of cutaneous melanoma. They may be present in patients with multiple melanocytic nevi (atypical nevus syndrome) or isolated and in small numbers in a non-familial context. The disease usually begins at puberty and ...
متن کاملFour Cases of Dysplastic Nevus Syndrome
Vol. 26 No. 4, 2014 547 Received June 4, 2013, Revised September 9, 2013, Accepted for publication September 13, 2013 Corresponding author: Seok-Jong Lee, Department of Dermatology, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 700-721, Korea. Tel: 82-53-420-5838, Fax: 82-53-426-0770, E-mail: [email protected] This is an Open Access article distributed under the terms...
متن کاملDysplastic nevus--risk factor or disguise for melanoma.
Dysplastic nevus is an acquired or hereditary nevus that clinically seems atypical and pathohistologically dysplastic. The term of dysplastic nevus has changed through history and even until now the dermatologists and pathologists have not found the same conclusion for name and definition of dysplastic nevus. Epidemiology of dysplastic nevus is different depending on geographic lattitude, being...
متن کاملDysplastic Nevus: A Fake Lesion?
The story of “dysplastic nevus” dates as far back as 1978 when W.H. Clark and colleagues [1] reported a group of melanocytic lesions with atypical clinical and histological features. Such melanocytic nevi were regarded as precursors of melanoma in patients with multiple nevi and/or family history of melanoma and the term of “dysplastic nevus” soon after entered the diagnostic jargon. The concep...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1980
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19801015)46:8<1787::aid-cncr2820460816>3.0.co;2-s